Adaptive Optical System for Photothermal Microscopy
نویسندگان
چکیده
منابع مشابه
Photothermal microscopy: optical detection of small absorbers in scattering environments.
Photothermal microscopy enables detection of nanometer-sized objects solely based on their absorption. This technique allows efficient observation of various nano-objects in scattering media notably gold nanoparticles in cells. The extreme sensitivity of the method and the stability of the signals open numerous applications in spectroscopy, analytical chemistry and bioimaging. This review brief...
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I developed a wideband low-noise optical beam deflection sensor with a photothermal cantilever excitation system for liquid-environment atomic force microscopy. The developed sensor has a 10 MHz bandwidth and 4.7 fm/sq.rt.Hz deflection noise density in water. The theoretically limited noise performance (i.e., the noise level limited only by the photodiode shot noise) has been achieved in liquid...
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We studied the phenomenon of photothermal bleaching - a gradual reduction of contrast agent particles during repeated scans in photoacoustic microscopy. The dependence of the photothermal bleaching rate on the excitation pulse energy, pulse duration, and the absorber's size was determined while the laser focal diameter was held constant. Our results showed that, the dependence of the phototherm...
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We demonstrate that the quantum-mechanical description of Rutherford scattering has a photonic counterpart in a new form of single particle photothermal microscopy. Using a split detector we provide experimental evidence that photons are deflected by a photothermal potential that is created by a local refractive index change around a heated nanoparticle. The deflection experienced is shown to b...
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ژورنال
عنوان ژورنال: Microscopy and Microanalysis
سال: 2020
ISSN: 1431-9276,1435-8115
DOI: 10.1017/s1431927620000288